If like many other people you use the excellent Widget Logic to control which URLs your sidebar content displays on, this may come in handy for you.
How do I know this?
I just spent a solid 2 hours looking for it myself!
If you want content to appear on the homepage only the code to enter into the Widget Logic field is:
is_home()
Everyone knows that though, right?
Well, if you display your latest posts on the homepage and only want a particular widget to display on the front page not paginated versions e.g.
http://www.yourdomain.com/page/2
Then the code you need is this:
is_home() && $post==$posts[0] && !is_paged()
Hope that helps someone out! 
Ping me a comment if you make good use of it. Always cool to know.
Cool man, thank you very much, It is exactly I was looking for. I use it for shop page (woocommerce) and it works great too:
is_shop() && $post==$posts[0] && !is_paged()
Thanks alot.. This was very helpful, You really saved me like days of research. Lol!!